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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Radiotherapy (12):
Recent article
Radiotherapy
Abstract
We reviewed the literature on their use and implications in urological practice....
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PMID: 21849189
PDF is available here.
PDF is available here.
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Abstract
We report an unusual, rare case of primary epithelioid rhabdomyosarcoma of a lymph node in the parotid basin. A 72-year-old man with a history of squamous cell carcinoma of the forehead and cheek had a 5-cm mobile nontender mass of the parotid tail and right level II region. A positron emission tomog...
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PMID: 21917681
PDF is available here.
PDF is available here.
New England Journal of Medicine (365)14 2011
Abstract
Abstract
Abstract
Abstract
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... (55)4 2011
Abstract
Bone metastases are responsible for most of the morbidity and mortality associated with solid malignant tumors, occurring in about 65-70% of the patients with advanced breast or prostate cancer. The pathophysiology of skeletal metastasis is a complex process that involves several bio...
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PMID: 21738116
PDF is available here.
PDF is available here.
Abstract
We review the case of an adolescent who presented with flank pain, fatigue and a discrete nonfunctioning adrenal lesion which was found to be an adrenal Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET). The patient was treated with a minimally invasive adrenalectomy as a component of multimod...
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PMID: 21681923
PDF is available here.
PDF is available here.
Abstract
We review the pathogenesis and current treatments of B-cell lymphoproliferative disorders and assess the role of rituximab for potential therapy in the setting of refractory CLH. We describe a case of CLH that was treated with intralesional rituximab. The patient had notable clinical improvement ove...
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PMID: 21658657
PDF is available here.
PDF is available here.
Medical Physics (38)6 2011
Abstract
To investigate how using different sets of decision criteria impacts the quality of intensity modulated radiation therapy (IMRT) plans obtained by multiobjective optimization.
A multiobjective optimization evolutionary algorithm (MOEA) was used to produce sets of IMRT...
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PMID: 21815370
PDF is available here.
PDF is available here.
Clinical Cancer Research (17)12 2011
Abstract
The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, irinotecan and temozolomide for the treatment of newly diagnosed glioblastoma has moderate toxicity and may improve efficacy compared with historical controls. The results from phase III trials are re...
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PMID: 21531816
PDF is available here.
PDF is available here.
Abstract
PET/CT has proven extremely useful in the management of melanoma patients, with great sensitivity (Se), but it tends to give false-positive results. Whole-body MRI (wb-MRI) is a new method that has made considerable progress.
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PMID: 21570561
PDF is available here.
PDF is available here.
Abstract
Abstract
Clinical Breast Cancer (11)1 2011
Abstract
The purpose of this study is to assess the impact of adjuvant therapy on survival in males with non-metastatic breast cancer.
A retrospective analysis of male breast cancers treated between 1990 and 2003 was performed. Age, estrogen and progesterone receptor (ER/PgR)...
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PMID: 21421521
PDF is available here.
PDF is available here.
Clinical Breast Cancer (11)1 2011
Abstract
We present an unusual case of radiation-induced morphea (RIM) that occurred after accelerated partial breast irradiation (APBI) using intracavitary Contura brachytherapy. A 65-year-old white woman was treated for stage IIA invasive ductal carcinoma of the left breast with APBI to a dose of 34 Gy in...
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PMID: 21421525
PDF is available here.
PDF is available here.
Abstract
We conducted a phase II single-institution trial of two cycles of induction chemotherapy with gemcitabine and carboplatin followed by high-dose conformal radiation concomitant with weekly paclitaxel and carboplatin in 39 patients. The trial required a dedicated tumor biopsy before treatment initiati...
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PMID: 21289520
PDF is available here.
PDF is available here.
Abstract
Gastrointestinal tract is the most common extranodal site involved by lymphoma with the majority being non-Hodgkin type. Although lymphoma can involve any part of the gastrointestinal tract, the most frequent sites in order of its occurrence are the stomach followed by small intestine and ileocecal r...
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PMID: 21390139
PDF is available here.
PDF is available here.
Abstract
MYCN amplification prevents cellular differentiation and promotes mitotic and karyorrhectic activities in neuroblastomas. Hence, MYCN-amplified tumors typically show an appearance of neuroblastoma of either an undifferentiated or a poorly differentiated subtype with a high mitosis-karyorrhexis index....
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PMID: 21288077
PDF is available here.
PDF is available here.
Anti-Cancer Drugs (22)2 2011
Abstract
We present an institutional series of risk adapted adjuvant therapy. Sixty evaluable patients who had received treatment with neoadjuvant fluoropyrimidine radiotherapy and surgery now received adjuvant fluoropyrimidines in the case of pT0-2N0 or oxaliplatin based combination in the case of pT3-4 or...
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PMID: 21218606
PDF is available here.
PDF is available here.
Anti-Cancer Drugs (22)2 2011
Abstract
The aim of this meta analysis was to evaluate the benefit of adding concomitant trastuzumab to neoadjuvant(anthracycline and taxane-based) chemotherapy, which was assessed based on two published randomized controlled trials. The eligible patients were randomized to receive either neoadjuvant chemoth...
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PMID: 21218604
PDF is available here.
PDF is available here.
Abstract
Presentation of techniques and procedures for regional chemotherapy in the treatment of unresectable liver metastases from different primary tumors as a modality of interdisciplinary therapy management. Such transarterial therapy methods include hepatic arterial infusion (HAI), transarterial chemoem...
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PMID: 21113865
PDF is available here.
PDF is available here.
Abstract
Advances in medical knowledge and treatment have resulted in improved five-year survival rates for some forms of cancer. However, pain syndromes resulting from chemotherapy, radiotherapy, surgery or interventional procedures continue to have a significant effect on cancer survivors'...
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PMID: 21329131
PDF is available here.
PDF is available here.
Abstract
Excess adiposity is a complication of childhood acute lymphoblastic leukaemia (ALL) and is commonly attributed to cranial radiation (CRT) administration. Hyperleptinaemia also occurs during ALL treatment, but there are no data on long-term alterations to adipocytokines following trea...
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PMID: 21464554
PDF is available here.
PDF is available here.
Abstract
Breast conservation surgery followed by whole breast irradiation has been established as a standard of care for the treatment of early stage breast cancer and is associated with excellent local control and overall survival. As most in-breast recurrences occur in the area surrounding...
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PMID: 20868345
PDF is available here.
PDF is available here.
Abstract
We report a case of t-ALL with t(11;19)(q23;p13.3) and MLL-MLLT1 (alias ENL) gene rearrangement confirmed by cytogenetic analysis, multiplex reverse transcription-PCR (multiplex RT-PCR), and DNA sequencing in a patient who had undergone treatment for breast cancer. A 40-yr-old woman developed acute...
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PMID: 21239865
PDF is available here.
PDF is available here.
Abstract
Abstract
We found no significant associations between exon 5 and exon 6 GSTP1 gene polymorphisms and response to therapy or overall survival. Patients carrying both variant exon 5 (Ile/Val or Val/Val) and variant exon 6 (Ala/Val) genotypes had significantly shorter TTP (5 vs. 8 months, p = 0.04). Moreover, p...
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PMID: 21766492
PDF is available here.
PDF is available here.
Abstract
With a mean follow up of 46.9-33.6 months (range 7-120), the 5-and 8-year OS rates were 70.0% and 61.5%, respectively. At the time of evaluation 119 (60.1%) patients had no evidence of disease. Among 79 patients who failed therapy, most of them (n=61; 77.2%) had local failure only. According to hist...
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PMID: 21766500
PDF is available here.
PDF is available here.
Clinical Neuropathology (30)3 2011
Abstract
Abstract
Lung cancer continues to be the leading cause of cancer-related mortality and approximately 70% of patients present with locally advanced or metastatic disease at the time of diagnosis. More than 50% of lung cancer cases are diagnosed in patients over the age of 65 years. The doublet...
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PMID: 21520993
PDF is available here.
PDF is available here.
Molecular Carcinogenesis (50)1 2011
Abstract
The major aspect contributing to the mortality of melanoma is its ability to spread, or metastasize. Ultraviolet B light (UVB) is considered an indirect cause of melanoma formation. However, little is known about the potential effects of UVB to melanoma metastasis. Integrins, a large family of cell...
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PMID: 21061269
PDF is available here.
PDF is available here.
Abstract
The emergence of molecularly targeted therapy did not spare head and neck cancers. Head and neck squamous cell carcinomas (HNSCC) were indeed one of the first tumor types to get a molecularly targeted agent approved (cetuximab, a monoclonal antibody targeting EGFR), not only in the recurrent or meta...
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PMID: 21134823
PDF is available here.
PDF is available here.
Abstract
The role of radiation therapy in metastatic disease has evolved from palliative to potentially curative intent for selected oligometastases using highly conformal radiation techniques, including extracranial stereotactic body radiotherapy (SBRT) in the last decade. SBRT has a potential to use small...
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PMID: 21220224
PDF is available here.
PDF is available here.
Abstract
Management of adverse events related to cancer therapies are seen as tertiary prevention. Concerning prostate cancer, dealing with secondary effects of treatments is crucial. Indeed, if recent advances in cancer therapy have lead to an acceptable overall prognosis, these results face increasing case...
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PMID: 21220229
PDF is available here.
PDF is available here.
Abstract
We retrospectively reviewed 389 differentiated thyroid carcinoma patients who underwent a total thyroidectomy and received high-dose RAI from January 2003 through December 2005. The patients were classified according to surveillance DxWBS findings and TSH-stimulated Tg levels 6 to 12 months after th...
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PMID: 21179279
PDF is available here.
PDF is available here.
Abstract
We show that LCK (lymphocyte-specific protein tyrosine kinase) is involved in the fractionated radiation-induced expansion of the glioma-initiating cell population and acquisition of resistance to anticancer treatments. Fractionated radiation caused a selective increase in the activity of LCK, a Src...
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PMID: 20971076
PDF is available here.
PDF is available here.
Abstract
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma in the United States. Historically, radiation therapy (RT) was the primary treatment for patients with localized disease. Several randomized trials have demonstrated that the addition of systemic therapy improve...
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PMID: 21192559
PDF is available here.
PDF is available here.
Abstract
To compare intensity-modulated radiotherapy (IMRT) treatment plans generated by segmental multileaf collimator (SMLC) and helical tomotherapy (HT) techniques for patients with unresectable sinonasal cancer.
SMLC-IMRT and HT-IMRT plans for 5 patients with cancer of the paranasal sinuses and nasal cav...
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PMID: 20142725
PDF is available here.
PDF is available here.
Abstract
To report a patient with a tumor-like corneal keloid.
Retrospective review of clinical features and histopathologic findings.
A 68-year-old woman with a remote history of an orbital tumor treated with radiation developed a corneal tumor. A biopsy of the tumor showed fibrocellular tissue, and her bli...
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PMID: 20856108
PDF is available here.
PDF is available here.
Abstract
We do not advocate elective nodal irradiation, even for those with bulky T2B malignancies. The addition of concomitant weekly cisplatin 30 mg/M² is considered for patients with T2B cancers. Open parotid laryngectomy is reserved for salvage of suitable patients with a local recurrence....
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PMID: 20051812
PDF is available here.
PDF is available here.
Abstract
Besides photons and electrons, high-energy particles like protons, neutrons, ⁴He ions or heavier ions (C, Ne, etc) have been finding increasing applications in the treatment of radioresistant tumors and tumors located near critical structures. The main difference between photons and hadrons is the...
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PMID: 20395789
PDF is available here.
PDF is available here.
Abstract
Despite evidence that radiation therapy (RT) improves outcome in multiple malignancies, some patients with strong clinical indications still refuse RT. Data on factors associated with RT refusal are limited. Furthermore, the effect of RT refusal on outcome has not been clearly defined.
Patients with...
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PMID: 20216302
PDF is available here.
PDF is available here.
Abstract
We studied whether 3D CRT could maintain survival and increase local-regional tumor control whereas reducing the morbidity and severity of radiation toxicity in patients with early primary nasopharyngeal carcinoma (NPC).
Patients with histologically proven keratinizing or nonkeratinizing undifferent...
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PMID: 20051809
PDF is available here.
PDF is available here.
Abstract
To use the Surveillance, Epidemiology, and End Results (SEER) registry to analyze age-specific time trends in the use of radiotherapy (RT) (external beam radiotherapy [EBRT], brachytherapy [brachy], and combination therapy [combo]) as first-line treatment for prostate cancer.
A total of 820,649 pros...
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PMID: 20051808
PDF is available here.
PDF is available here.
Abstract
To determine the pattern of failures following intensity modulated radiation therapy for head and neck cancer.
A retrospective single institution study. Between May 2001 and June 2008, 176 patients with head and neck cancer were treated with intensity modulated radiation therapy at Fox Chase Cancer...
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PMID: 21063195
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Complete tumor regression may develop after neoadjuvant chemoradiation therapy for distal rectal cancer. Studies have suggested that selected patients with complete clinical response may avoid radical surgery and close surveillance may provide good outcomes with no oncologic compromise. However, def...
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PMID: 21178866
PDF is available here.
PDF is available here.
Abstract
We compared the outcome of patients with mural complete pathological response (n = 37) who underwent radical surgery (group I) and those (n = 14) who had local excision only (group II). With a median follow-up of 48 months, 4 patients in group I had a recurrence and none in group II had a recurrence...
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PMID: 21178856
PDF is available here.
PDF is available here.
Abstract
Samarium-153 ethylenediamine tetramethylene phosphoric acid (153Sm-EDTMP) is a radiopharmaceutical that has been used to treat osteosarcoma. The authors conducted a phase 2 study to test safety and response of high-risk osteosarcoma to tandem doses of 153Sm-EDTMP and to determine cor...
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PMID: 20715156
PDF is available here.
PDF is available here.
Abstract
The increasing incidence of radiation-induced sarcoma (RIS) has become a significant problem that can limit long-term survival. The objective of the current study was to analyze the clinicopathologic characteristics, treatment outcomes, and prognostic factors of RIS after radiotherap...
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PMID: 20715161
PDF is available here.
PDF is available here.
Abstract
Data regarding costs of prostate cancer treatment are scarce. This study investigates how initial treatment choice affects short-term and long-term costs.
This retrospective, longitudinal cohort study followed prostate-cancer cases diagnosed in 2000 for 5 years using...
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PMID: 20734396
PDF is available here.
PDF is available here.
Abstract
We report the case of a 60-year-old woman with multiple lymph node metastases after ascending colon cancer who received radiation therapy and then chemotherapy with S-1. She was diagnosed with lymph node metastasis of the para aorta and left upper clavicle 10 months after surgery. We performed radia...
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PMID: 21160273
PDF is available here.
PDF is available here.
Chemical Communications (46)42 2010
Abstract
Lead(II)-texaphyrins and the first discrete binuclear μ-oxo bismuth(III)-texaphyrin are reported. The latter was characterized via single crystal X-ray diffraction analysis. Cell proliferation assays using the A2780 ovarian cancer cell line were used to determine the cytotoxicity of the complexes....
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PMID: 20922235
PDF is available here.
PDF is available here.
Abstract
This novel radioactive tracking technology has the potential to be useful in accurate target localization and real-time monitoring for radiation therapy.
Copyright © 2010 Elsevier Inc. All rights reserved....
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PMID: 20615628
PDF is available here.
PDF is available here.
Abstract
On average, the hippocampal avoidance volume was 3.3 cm(3), occupying 2.1% of the whole-brain planned target volume. Helical tomotherapy spared the hippocampus, with a median dose of 5.5 Gy and maximum dose of 12.8 Gy. LINAC-based IMRT spared the hippocampus, with a median dose of 7.8 Gy and maximum...
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PMID: 20598457
PDF is available here.
PDF is available here.
Abstract
We have compared these techniques in terms of the plan quality, planning efficiency and delivery efficiency. Fourteen patients were selected for this study including six head-and-neck (HN) cases, and two cases each of prostate, pancreas, lung and partial brain. For each case, three VMAT plans were c...
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PMID: 20959688
PDF is available here.
PDF is available here.
Abstract
Recently, ion beam radiotherapy (including protons as well as heavier ions) gained considerable interest. Although ion beam radiotherapy requires dose prescription in terms of iso-effective dose (referring to an iso-effective photon dose), absorbed dose is still required as an operative quantity to...
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PMID: 20952816
PDF is available here.
PDF is available here.