Abstract
We report that insertion of the ND into the cloaca is an unrecognized but crucial step that is required for proper positioning of the ureter and that depends on Ret signaling. Analysis of Ret mutant mice at birth reveals hydronephrosis and defective ureter maturation, abnormalities that our results...
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PMID: 21521737
PDF is available here.
Abstract
We investigated ATP release from uroepithelial cells infected with bacteria and the effect of ATP on the host cell proinflammatory interleukin 8 (IL-8) response. The human kidney epithelial cell line A498 and the human uroepithelial cell line UROtsa were grown in culture and stimulated by the uropat...
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PMID: 20515921
PDF is available here.
Abstract
During a 10-year period of the present study, 35 new cases of urinary tract TB were diagnosed, with a male/female ratio of 1.3:1 and a common age group of 31-40 years. 34.3% of the patients were farmers. The most presenting symptoms were polyuria, dysuria and acidic urinary pH with pyuria. 80% ofthe...
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PMID: 20718167
PDF is available here.
Abstract
We tested whether urinary CD80 excretion might distinguish between patients with MCD from those with FSGS. Urinary CD80 was measured in 17 patients with biopsy-proven MCD and 22 with proven FSGS using a commercially available enzyme-linked immunosorbent assay and its molecular size determined by wes...
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PMID: 20485332
PDF is available here.
Abstract
We screened 11 inbred mouse strains for reflux and kidney size and identified one strain, C3H/HeJ, that has a 100 percent incidence of vesico-ureteric reflux with otherwise normal kidneys at birth. These mice are predisposed to reflux as a result of a defective uretero-vesical junction characterized...
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PMID: 20407478
PDF is available here.
Abstract
This is the largest report of GU injuries during any military conflict. The distribution and percentage of casualties with GU injuries in the OCO are similar to those of previous conflicts. Consideration should be given to personnel protective equipment for the areas associated with GU injuries and...
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PMID: 20622614
PDF is available here.
Abstract
Fetal diagnosis prompts the question for fetal therapy in highly selected cases. Some conditions are suitable for in utero surgical intervention. This paper reviews historically important steps in the development of fetal surgery. The first invasive fetal intervention in 1963 was an intra-uterine bl...
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PMID: 20572114
PDF is available here.
Abstract
We outline common conditions that produce LUTD in children; discuss difficulties encountered in assessing the need for surgical treatment; provide an overview of the surgical procedures available; and consider the evidence for and against surgical intervention before, during, and after renal transpl...
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PMID: 20535849
PDF is available here.
Abstract
Anorectal malformations (ARMs) and Hirschsprung disease (HD) are the most common congenital colorectal defects in the newborn. The outcomes of HD and ARMs have improved significantly because of improved understanding of the pathologic anatomy and physiology of these defects and of the modern surgica...
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PMID: 20307853
PDF is available here.
Abstract
The human urinary tract represents an impressive mechanical barrier against infection. Its immediate anatomical proximity to the gastrointestinal tract predisposes it to invasion and infection by enteric bacteria. Thus the immune system of the urinary tract represents an essential and powerful means...
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PMID: 20414764
PDF is available here.
Abstract
Ultrasound detected most structural abnormalities except grade III reflux. Since it is noninvasive, ultrasound has a place in the evaluation of infants with urinary tract infection, especially in the absence of prenatal ultrasound during late pregnancy. Kidney length in infants with acute infection...
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PMID: 20303537
PDF is available here.
Abstract
Genetic-and molecular-based postulates regarding the pathogenesis of the renal cystic and developmental diseases have implicated mutated master genes and the modification of genes that are crucial in renal development and genes that are central to the sensory effects of the renal tubular primary cil...
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PMID: 20367308
PDF is available here.
Abstract
Gynecologic surgery often entails meticulous dissection in areas close to the bladder, rectum, ureters and major vessels of the pelvis. The close anatomical relationship between these bodies that frequently makes are affected during pelvic surgery. When a complication occurs, it is vital to recogniz...
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PMID: 20939231
PDF is available here.
Abstract
We have therefore emphasized the situations when animal models are required to investigate lower urinary tract disorders and what they should set out to achieve. In particular we have discussed the merits and disadvantages of a number of paradigms that set out to investigate specific lower urinary t...
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PMID: 20432320
PDF is available here.
Abstract
Powerful advances in central nervous system (CNS) imaging technology offer an unprecedented opportunity to identify which CNS structures coordinate lower urinary tract (LUT) function in health and disease. Positron emission tomography and functional magnetic resonance imaging studies have already yi...
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PMID: 20432326
PDF is available here.
Abstract
Primary localized amyloidosis of the upper urinary tract is a rare condition that is of interest because the clinical presentation and radiographic and endoscopic appearance mimic malignancy. Many commonalities exist between upper urinary tract and bladder amyloidosis, but obstructive features, like...
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PMID: 20218886
PDF is available here.
Abstract
Maternal OC use during the first 3 months of pregnancy was associated with an increased odds ratio for 2 of 32 birth defects: hypoplastic left heart syndrome (adjusted odds ratio = 2.3 [95% confidence interval = 1.3-4.3) and gastroschisis (1.8 [1.3-2.7]). CONCLUSION: Previous reports of associations...
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PMID: 20087193
PDF is available here.
Abstract
The prevalence of renal anomalies in neonates with isolated SUA is low. We suggest that routine ultrasound screening for renal anomalies is not warranted in neonates with isolated SUA.
Copyright 2009 S. Karger AG, Basel....
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PMID: 19887850
PDF is available here.
Abstract
Normal lower urinary tract function consists of voiding and storage. During voiding, the pontine micturition reflex center orders the sacral parasympathetic nucleus to increase parasympathetic activity, resulting in urinary bladder detrusor contraction via activation of post-synaptic muscarinic rece...
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PMID: 20134111
PDF is available here.
Abstract
A sociological study was made of quality of life of 60 patients with nephrostomic drainage and 71 patients with an ureteral stent according to standard international questionnaires SF-36 and EORTC QLQ-C30, version 3.0. It was found that both internal and external drain significantly aggravate qualit...
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PMID: 20967990
PDF is available here.
D Broniszczak,
H Ismail,
P Nachulewicz,
M Szymczak,
T Drewniak,
M Markiewicz-Kijewska,
A Kowalski,
K Jobs,
E Smirska,
J Rubik,
L Skobejko-Włodarska,
P Gastoł,
A Mikołajczyk and
P Kalicinski
Abstract
Kidney transplantation in children with lower urinary tract dysfunction and end-stage renal failure offers excellent medium term results in our experience, despite the creation of non-standard urinary drainage. Recurrent urinary tract infections are the most common complications in these patients, b...
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PMID: 19866413
PDF is available here.
Abstract
We think that all HK associated with UA should be controlled, as above 50% are subsidiaries of surgical correction. The hydronephrosis can be obstructive over the time and it could be necessary to check them for a long time....
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PMID: 20578575
PDF is available here.
Abstract
There were no statistically significant differences in age, gender, history of urinary tract infections or functional voiding disorders between these two groups. All of the studied subjects had normal BP and GFR. Renal ultrasound was abnormal only in BEN offspring (6.66%) as well as increased urine...
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PMID: 20499501
PDF is available here.
Abstract
Most cases of candidiasis have been attributed to C. albicans, but recently, non- Candida albicans Candida (NCAC) species have been identified as common pathogens. The ability of Candida species to form biofilms has important clinical repercussions due to their increased resistance to antifungal the...
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PMID: 19888800
PDF is available here.
Abstract
Of the 31,380 patients with pelvic fractures, 1,444 had GUI. Men more commonly sustained pelvic fractures with GUI than women (66.14% vs. 33.86%). The incidence of urogenital, bladder, and urethral injuries for men and women was 5.34%, 3.41%, 1.54%, and 3.62%, 3.37%, 0.15%, respectively. Patients wi...
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PMID: 19901665
PDF is available here.
Abstract
389 of 142 986 (2.7 per 1000) live born children had malformations of the kidneys and/or urinary tract. The prevalence was higher for children born in the period 1997-2006 (241/70 217; 3.4 per 1000) than in 1987-1996 (148/72 769; 2.0 per 1000), p< 0.0011. The percentage of children with anomalies di...
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PMID: 19823200
PDF is available here.
Abstract
PUV represents a spectrum of disease severity. A normal prenatal ultrasound does not preclude PUV. The majority of patients with a normal prenatal examination have good outcomes. The OR suggests that there may be increased risk for poor outcome in those with an abnormal prenatal examination. A multi...
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PMID: 19632082
PDF is available here.
Abstract
In every case of terminated pregnancy and death after birth the autopsy revealed additional renal or exstrarenal anomaly which were not prenataly detected. Postnatal evaluation of survived children with unilateral multicistic disease revealed that 31.4% of them have an anomaly of the contralateral k...
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PMID: 19877553
PDF is available here.
Abstract
A microdeletion of 6p25.3, identified in mother and one fetus, is not associated with a gene known to be involved in urethral development and therefore of unknown significance.
(c) 2009 Wiley-Liss, Inc....
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PMID: 19551712
PDF is available here.
Ching-Chia Li,
Hsun-Shuan Wang,
Wen-Jeng Wu,
Yii-Her Chou,
Chia-Chu Liu,
Cheng-Yu Long,
Shih-Cheng Hus,
Chieh-Han Chuang,
Mei-Yu Jang,
Shu-Pin Huang,
Yung-Shun Juan and
Chun-Hsiung Huang
Abstract
OBJECTIVE To describe the technique of laparoscopic complete urinary tract exenteration (LaCUTE), where specimens are withdrawn en bloc through the vagina, and to compare our results for patients had this procedure with those who had surgery by traditional open methods PATIENTS AND METHODS From Febr...
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PMID: 19154504
PDF is available here.
Abstract
From the literature survey it appears that transient first-trimester cysts are not associated with chromosomal anomaLies, yet they might be associated with congenital maLformations, especially those of the abdominal wall and the urinary tract, and should lead to further detailed sonographic evaluati...
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PMID: 19848330
PDF is available here.
Abstract
Although it becomes vitally important only after birth, renal function already plays significant role in maintaining fetal metabolic equilibrium. The kidneys significantly contribute to production of amniotic fluid. Adequate amount of amniotic fluid is needed to stimulate the intrauterine fetal resp...
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PMID: 19739276
PDF is available here.
Abstract
Uropathogenic Escherichia coli (UPEC) can grow in environments with significantly elevated osmolarities, such as murine and human urinary tracts. OmpR is the response regulator part of a two-component OmpR-EnvZ regulatory system that responds to osmotic stresses. To determine the role of OmpR in UPE...
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PMID: 19383700
PDF is available here.
Abstract
The purpose of this study was to assess the feasibility and safety of magnetic resonance imaging (MRI)-guided PCN in an open-configuration low-field MRI system. Eight patients were prospectively enrolled in the study. The degree of the dilatation of the renal collecting system varied from minimal to...
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PMID: 19034458
PDF is available here.
Abstract
There is a low rate of detectable renal abnormalities in infants with a normal postnatal sonogram at 4-6 weeks of age. Routine prophylactic antibiotics are not indicated in infants with isolated antenatal hydronephrosis. Infants with a multicystic dysplastic kidney and a normal contralateral kidney...
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PMID: 19663038
PDF is available here.
Abstract
Particle motion in an unsteady peristaltic fluid flow is analyzed. The fluid is incompressible and Newtonian in a two-dimensional planar geometry. A perturbation method based on a small ratio of wave height to wavelength is used to obtain a closed-form solution for the fluid velocity field. This ana...
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PMID: 19518250
PDF is available here.
Abstract
Mucopolysaccharidosis type IIIB (MPS IIIB; Sanfilippo syndrome type B) is a metabolic disorder with devastating clinical characteristics starting in early childhood and leading to premature death. A knockout mouse strain was developed that models this disease. Mice of the strain B6.129S6- Naglu(tm1E...
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PMID: 19389305
PDF is available here.
Abstract
We propose that receptor antibodies need better validation before they can reliably be used....
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PMID: 19198807
PDF is available here.
Abstract
Two hundred and twenty seven patients (121 men, 39 women, and 67 children) underwent genito-urinary reconstruction during the seven years spanning 1991-1998. The study population consisted of 160 adults and 67 children (< 15 years old). Mean patient age was 43 years with a range of 18-87 years for a...
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PMID: 19761178
PDF is available here.
Abstract
We designed a prospective study aimed at determining the prevalence of CAKUT in HSCR patients and at identifying RET, glial cell line-derived neurotrophic factor (GDNF), and GDNF family receptor alpha1 (GFRalpha1) mutations or haplotypes associated with this subset of HSCR patients. Eighty-four HSCR...
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PMID: 19282698
PDF is available here.
Abstract
We report on preliminary investigations into using Raman tweezers to classify urological cell lines. This builds on earlier work within the group, whereby Raman tweezer methodologies were developed, and the application of this technique to differentiate between live prostate cancer (CaP) and bladder...
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PMID: 19343685
PDF is available here.
Abstract
We report the aetiology and outcomes over 5 years, during which period the improving socio-economic situation has allowed increasing provision of dialysis and transplantation. The records of 205 children (124 male; 60.5%) who were referred to a tertiary paediatric nephrology unit in Khartoum between...
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PMID: 18958501
PDF is available here.
Abstract
We explore the pharmacology of duloxetine in the nervous system and lower urinary tract, and the evidence for its use in the management of women with urinary incontinence....
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PMID: 19503763
PDF is available here.
Abstract
An established standardized terminology is necessary for communication of scientific information, and for prevention of mistreatment and misdiagnosis. Terminology concerning the lower urinary tract has been much discussed; in particular, the meaning of terms like lower urinary tract...
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PMID: 19151894
PDF is available here.
Abstract
We have developed prognostic criteria of efficacy of PUI roentgenoendoscopic treatment which was effective in short strictures (obliterations) of the UUT in relatively intact renal function, absence of manifest UUT hypotension, when performed 3 weeks to 3 months after iatrogenic injury....
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PMID: 19526871
PDF is available here.
Abstract
The aim of this study was to determine if pelvic floor muscle training (PFMT) improves lower urinary tract function in people with multiple sclerosis (MS). The authors found that a nine-week PFMT programme improved the function of the PFM, reduced the symptoms associated with lower urinary tract dys...
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PMID: 19326656
PDF is available here.
Abstract
We recently detected UMOD mutations in two patients with CAKUT. As HNF1B and UMOD act in the same pathway and cause similar phenotypes, we here examined whether UMOD mutations would be found in patients with CAKUT. Mutation analysis of UMOD was performed in 96 individuals with CAKUT by direct sequen...
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PMID: 18846391
PDF is available here.